Drug Discovery Chemistry, Fragment-Based Drug Discovery Conference, San Diego, California
From Fragment Hit to Lead to Optimization to Small Molecule Drug Candidate
Cambridge Healthtech Institute’s 17th Annual
APRIL 19-20, 2022, San Diego, California
Red Glead Discovery are giving a talk at:
The advantages of WAC for FBS are the detection of weak binders by screening fragments at low concentrations (<5 μM) and immediate ranking of hits. Here we present the results of a WAC screen towards SMARCA4 as well as subsequent hit validation and expansion efforts.