Drug Discovery Chemistry, Fragment-Based Drug Discovery Conference, San Diego, California

From Fragment Hit to Lead to Optimization to Small Molecule Drug Candidate

Cambridge Healthtech Institute’s 17th Annual

APRIL 19-20, 2022, San Diego, California


Red Glead Discovery are giving a talk at:


Kirill Popov, PhD, Head of FBLD, Weak Affinity Chromatography WAC

The advantages of WAC for FBS are the detection of weak binders by screening fragments at low concentrations (<5 μM) and immediate ranking of hits. Here we present the results of a WAC screen towards SMARCA4 as well as subsequent hit validation and expansion efforts.