Producing peptides for research and therapeutic applications is a challenging task. By combining our excellence in peptide design and synthesis strong competence with in organic chemistry, Red Glead Discovery is able to provide exclusive peptides of the highest quality to academia and industry. We also offer design services addressing issues of biological activity, pharmacokinetic and physicochemical properties. This has been made possible by the recent acquisition of Pepticon, a specialised CRO company which is now owned by Red Glead Discovery.
Our unique combined capabilities enable first-rate delivery of peptides customised to your needs with respect to effective peptide syntheses, advanced chemical modifications and radioactive isotope labelling. In short, we offer:
Customised peptide design & synthesis
  • We routinely perform peptide synthesis using automated peptide synthesisers based on solid phase technologies with subsequent purification using preparative HPLC, additionally solution phase methods can be employed.
  • Up to 50 amino acids single chain peptides of high purity have been delivered using the current instruments. Using chemical ligation techniques, deliveries of up to 85 amino acid long peptides have been achieved. Different types of resins may be used depending on the need of the client.
  • Non-natural amino acids and other building blocks are introduced on a custom basis, e.g. glycopeptides. Our medicinal and peptide chemistry knowledge enables us to rationally introduce adequate modifications, such as amino acid substitutions (e.g. for solubility, stability, etc.), chemical modifications (e.g. for stability, structure-function studies), attachment of ligands (e.g. chromophores, affinity ligands) and conjugation of peptides to proteins and antibodies.
Peptide analysis
  • Quality control confirming chemical identity, amino acid sequence and amino-specific modifications is routinely performed on our produced peptides using HPLC, LC-MS, LC-MS/MS and NMR spectroscopy.
  • Quantitative NMR for accurate peptide concentration determination as well as quantification of salt, e.g. stoichiometry of acetate salts.
  • We have the expertise to perform more in-depth studies of 3D conformation and dynamic phenomena using multidimensional heteronuclear NMR techniques performed in-house.
Isotope labelling of peptides
  • We offer cost-effective labelling with stable isotopes (e.g. 2H, 13C, and 15N) as well as radioisotopes (e.g. 3H, 14C).
Peptide purification, isotope labelling and peptide analysis are also offered as stand-alone services.
Here you can fill out a simple form to get a quote for your peptide(s).